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Product Indentification

Name:   GSK1292263
Synonyms:    GSK1292263
CAS Registry Number:   1032823-75-8
Molecular Formula:   C23H28N4O4S
Molecular Weight:    456.56
Molecular Structure:    


                   In stock!


                  Appearance: white solid



                  Purity: 99%min



                  Storage:  -20 C



                  Inquiry (H1NMR,HPLC,LC-MS)




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Related pages:

     Search GSK1292263 in google
     Search CAS 1032823-75-8 in google
     Search C23H28N4O4S in google


Related info:


            GSK1292263 is a novel GPR119 receptor agonist used for the treatment of type 2 diabetes. G protein-coupled receptor 119 also known as GPR119 is a G protein-coupled receptor that in humans is encoded by the GPR119 gene. GPR119, along with GPR55 and GPR18, have been implicated as novel cannabinoid receptors. GPR119 is expressed predominantly in the pancreas and gastrointestinal tract in rodents and humans, as well as in the brain in rodents. Activation of the receptor has been shown to cause a reduction in food intake and body weight gain in rats. GPR119 has also been shown to regulate incretin and insulin hormone secretion. As a result, new drugs acting on the receptor have been suggested as novel treatments for obesity and diabetes.




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