About Us

Contact Us

Home About Us Product News Order Career Contact


           APIs&Intermediates Chemicals of Shanghai APIs Chemical Co., Ltd  


Product Indentification

Name:    Dapagliflozin
Synonyms:    BMS-512148
CAS Registry Number:   461432-26-8
Molecular Formula:   C21H25ClO6
Molecular Weight:    408.87
Molecular Structure:  



                     In stock!   Click for COA   50g in stock!



                    Appearance: white solid                 



                    Purity: 99%min



                    For Research Use Only







Related drugs for SGLT Target:


[ Pfizer; Lexicon(LX-4211); Roche(CSG-452, R-7201);Taisho(TS-071)]  >> Phase II


[BMS(Dapagliflozin); Mitsubishi Tanabe(Canagliflozin); Astellas(ASP-1941) ;Boehringer Ingelheim(BI-44847)]  >> Phase III



Related intermediates:







Related pages:

     Search Dapagliflozin or BMS-512148 in google
     Search CAS 461432-26-8  in google
     Search C21H25ClO6 in google


Related info:


       Dapagliflozin inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney. Blocking this transporter causes blood glucose to be eliminated through the urine. The efficacy of the this medication class has yet to be determined, but in initial clinical trials, dapagliflozin lowers HbA1c by 0.90 percentage points when added to metformin.




Home About Us Product News Order Career Contact
 Copyright @ 2010-2011 APIs All rights reserved