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           APIs&Intermediates Chemicals of Shanghai APIs Chemical Co., Ltd 

           

             

 

Product Indentification
 

 

Name:   JNJ-38877605
Synonyms:   JNJ-38877605
CAS Registry Number:   943540-75-8
Molecular Formula:   C19H13F2N7
Molecular Weight:    377.35
Molecular Structure:    

 

                 
                  In stock!

 

                 Appearance: white solid

 

                  Purity: 99%min

 

 

                  For Research Used Only

 

 

                  Inquiry

 

  

 

Related c-Met Inhibitors:

 

 

          AMG-208|1002304-34-8                                                                  Axitinib|319460-85-0   

 

         Foretinib|849217-64-7                                                                    JNJ-38877605|943540-75-8   

  

          MGCD-265|875337-44-3                                                               PF-04217903|956905-27-4

         
SGX-523|1022150-57-7                                                                  SU11274|658084-23-2

 

      849217-68-1|Cabozantinib                                                              PF-02341066|877399-52-5

 

      1000873-98-2|ARQ197

 

 

Related pages:


     Search  JNJ-38877605 in google
     Search CAS 943540-75-8 in google
     Search C19H13F2N7 in google

 

 

c-Met inhibitor JNJ-38877605 
      An orally available, small molecule inhibitor of the proto-oncogene c-Met (hepatocyte growth factor receptor [HGFR]) with potential antineoplastic activity. c-Met inhibitor JNJ-38877605 selectively binds to c-Met, thereby inhibiting c-Met phosphorylation and disrupting c-Met signal transduction pathways. This may induce cell death in tumor cells overexpressing c-Met protein or expressing constitutively activated c-Met protein. c-Met, a receptor tyrosine kinase overexpressed or mutated in many tumor cell types, plays key roles in tumor cell proliferation, survival, invasion, metastasis, and tumor angiogenesis.

 

 

                     

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