About Us

Contact Us

Add Favorite
Home About Us Product News Order Career Contact

                                                                                                            

           APIs&Intermediates Chemicals of Shanghai APIs Chemical Co., Ltd 

           

              ·

 

Product Indentification
 

 

Name:   Bendamustine HCl
Synonyms:   Treanda™,Bendamustinum;Bendamustina;DD6304600;SDX-105;4-(5-(bis(2- chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid; 2-Benzimidazolebutyric acid, 5-(bis(2-chloroethyl)amino)-1-methyl-;5-(Bis(2-chloroethyl)amino)-1-methyl-2-benzimidazolebutyric acid;1H-Benzimidazole-2-butanoic acid, 5-(bis(2-chloroethyl)amino)-1-methyl-.

4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid

CAS Registry Number:   3543-75-7 (HCl salt); 16506-27-2 (Free base))
Molecular Formula:   C16H22Cl3N3O2
Molecular Weight:    394.72
Molecular Structure:    

 

                    In stock!

 

                    Purity:99%min

 

 

                    Storage: 4 deg.                 

 

 

                    For Research Use Only

 

 

                    Inquiry (H1NMR,HPLC,LC-MS)

 

 

Related pages:

 


     Search Bendamustine HCl in google
     Search CAS 3543-75-7  in google
     Search C16H22Cl3N3O2  in google

 

 

 

Bendamustine was first synthesized in 1963 by Ozegowski and Krebs in East Germany (the former German Democratic Republic). It is a white, water soluble microcrystalline powder with amphoteric properties. Until 1990 it was available only in East Germany. East German investigators found that it was useful for treating chronic lymphocytic leukemia, Hodgkin’s disease, non-Hodgkin’s lymphoma, multiple myeloma and lung cancer.
 

Bendamustine received its first marketing approval in Germany, which is marketed under the tradename Ribomustin, by Astellas Pharma GmbH's licensee, Mundipharma International Corporation Limited, which it is indicated as a single-agent or in combination with other anti-cancer agents for indolent NHL, multiple myeloma, and CLL. SymBio Pharmaceuticals Ltd holds exclusive rights to develop and market bendamustine HCl in Japan and selected Asia Pacific Rim countries.

In March 2008, Cephalon received approval from the United States Food and Drug Administration to market bendamustine in the US, where it is sold under the tradename Treanda, for treatment of CLL.  In October 2008, the FDA granted further approval to market Treanda for the treatment of indolent B-cell non-Hodgkin's lymphoma (NHL) that has progressed during or within six months of treatment with rituximab or a rituximab-containing regimen.

 

 

 

 

 

 

 

 

Home About Us Product News Order Career Contact
 Copyright @ 2010-2011 APIs All rights reserved
 

 

 

No_Right_Click

 

No_Right_Click