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Product Indentification


Name:   Ruxolitinib
Synonyms:   INCB018424
CAS Registry Number:   941678-49-5
Molecular Formula:   C17H18N6
Molecular Weight:    306.37
Molecular Structure:    



                   In stock!





                   Storage: 4 deg C






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     Search Ruxolitinib in google
     Search CAS 941678-49-5  in google
     Search C17H18N6 in google


Related info: from wiki


     Ruxolitinib (trade name Jakafi, by Incyte Pharmaceuticals and Novartis) is a drug for the treatment of intermediate or high-risk myelofibrosis, a type of bone marrow cancer. It is also being investigated for the treatment of other types of cancer and for plaque psoriasis. It is a Janus kinase inhibitor with selectivity for subtypes 1 and 2 of this enzyme.

The phase III Controlled Myelofibrosis Study with Oral JAK Innhibitor-I (COMFORT-I) and COMFORT-II trials showed significant benefits by reducing spleen size, relieving debilitating symptoms, and improving overall survival. In November 2011, ruxolitinib was approved by the U.S. Food and Drug Administration for the treatment of intermediate or high-risk myelofibrosis based on results of the COMFORT-I and COMFORT-II Trials.



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