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Product Indentification
 

Name:   TW-37
Synonyms:   N-[4-[(2-tert-Butylphenyl)sulfonyl]phenyl]-2,3,4-trihydroxy-5-[(2-isopropylphenyl)methyl]benzamide

TW-37; Bcl-2 Inhibitor

CAS Registry Number:   877877-35-5
Molecular Formula:   C33H35NO6S
Molecular Weight:    573.70
Molecular Structure:    

                 

                  In stock!

 

                   Purity:99%min

 

                   Storage: 4 deg C

 

                   For Research Use Only

 

                  Inquiry

 

 

Related Bcl-2 inhibitor:

 

                   ABT-737|852808-04-9                                                                                         ABT263|923564-51-6         

 

                   Gossypol|90141-22-3|12542-36-8|Gossypol-acetic acid                        Obatoclax mesilate|803712-79-0

 

              TW-37|877877-35-5

 

 

Related pages:


     Search TW-37 in google
     Search CAS 877877-35-5   in google
     Search C33H35NO6S in google

 

 

 

Biological Activity


      Bcl-2 inhibitor (Ki values are 0.29 μM and 1.11 μM for Bcl-2 and Bcl-XL respectively). Inhibits the angiogenic potential of endothelial cells in vitro. Induces S-phase arrest and apoptosis in pancreatic cancer cell lines; also inhibits the activation of Notch-1 and Jagged-1 in vitro and in vivo.

 

 

 

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